William Spier was editor, producer, director. A lifelong radio man, he had broken in during the primitive days of 1929 and earned his stripes serving on such pioneering shows as The March of Time. Spier assembled the writing team of Bob Tallman and Ann Lorraine and began putting Spade together. He was impressed by the deep, cynical, tough qualities in Howard Duff's voice. Spier was also an American writer, producer, and director for television and radio. He is best known for his radio work, notably Suspense and The Adventures of Sam Spade. He was born in New York City to a Jewish father and a Presbyterian mother. Spier graduated from Evander Childs High School.
He eventually became the chief critic for the magazine Musical America at age 19.
In 1929, Spier was hired at the advertising agency Batten, Barton, Durstine and Osborn. At the agency, he produced and directed radio shows, such as The Atwater Kent Hour, an hour-long Sunday night presentation of Metropolitan Opera singers; General Motors' Family Party; and Ethyl Tune-Up Time. In 1936, he directed and co-wrote The March of Time program, hiring Orson Welles for his first job in radio. In 1940, Spier became chief of the writers' department and director of program development at the Columbia Broadcasting Company (CBS). At the same time, he was co-director, co-producer and some-time writer of Suspense, an anthology program of mysteries and thrillers, and Duffy's Tavern.
In 1941 Spier traveled to Los Angeles, which gave him access to a larger and better known talent pool. Guest stars for Suspense episodes included Lucille Ball, Cary Grant, Kirk Douglas, Joan Crawford, Bette Davis, Joan Fontaine, Judy Garland, Rita Hayworth, Marlene Dietrich, Richard Widmark and William Holden. Suspense had become increasingly popular; for the 1949–50 season, the program ranked number eight of the top 10 programs. The best known episode of the series was “Sorry Wrong Number,” starring Agnes Moorehead, in which a bed-ridden woman who by a chance incorrect phone connection overhears two men planning to murder a woman at 11:15 p.m. The episode was so popular that it was repeated eight times during the run of the series. The episode was even recorded on two 12-inch discs on Decca Records in 1943, becoming the number three most popular recording. The episode was eventually expanded for a successful film production, starring Barbara Stanwyck and Burt Lancaster.
In 1946, Spier directed, produced and sometimes wrote the radio series The Adventures of Sam Spade, based upon the detective created by Dashiell Hammett. Howard Duff starred as Sam Spade with Lurene Tuttle portraying his loyal secretary Effie. He also produced two anthology series: The Clock (radio) and The James and Pamela Mason Show. A 1949 magazine article said Spier "is generally rated radio's top-notch creator of suspense-type dramas.
In 1952, Spier introduced TV's first 90-minute show, Omnibus, for CBS. He produced Medallion Theatre on NBC in 1953–54. He created (with Louis Pelletier), produced, directed, and wrote for the 1954–1955 CBS situation comedy Willy, starring June Havoc. In some respects, the show was ahead of its time in that Havoc's character, Willa “Willy” Dodger, was an unmarried lawyer with her own legal practice in a small New England town. The show was a Desilu production, and like I Love Lucy, Willy was filmed before a live studio audience. Willy was broadcast at 10:30 p.m. on Saturdays opposite the popular NBC series, Your Hit Parade. Midway through the season, an attempt was made to increase ratings by having Havoc's character relocate to New York to represent show business clients; however, the show only lasted one season. In 1956, Spier produced three episodes of Man Against Crime. He subsequently limited his career in television to writing scripts for such television series as The Lineup, Peter Gunn and The Untouchables.
In 1954, Spier co-directed, with Roy Kellino, the film Lady Possessed, starring James Mason and Havoc, with a screenplay written by Mason and his wife, Pamela Mason, based upon her novel Del Palma.
Spier was married to Mary Scanlan from 1929 to 1939 and had three children with her: Peter, Greta, and Margaret. Spier died, aged 66, at the home he shared with Havoc in Weston, Connecticut.